Breast cancer recurrence rate not up with autologous fat transfer

Breast cancer recurrence rate not up with autologous fat transfer
(HealthDay)—For patients with breast cancer, reconstruction with autologous fat transfer (AFT) seems not to increase the rate of locoregional recurrence versus conventional breast reconstruction, according to a study published online Oct. 10 in JAMA Surgery.

Todor Krastev, M.D., Ph.D., from the Maastricht University Medical Center in the Netherlands, and colleagues matched 287 patients with 300 affected breasts receiving AFT between 2006 and 2014 to 300 nonexposed control patients based on age, type of oncologic surgery, tumor invasiveness, and disease stage. AFT patients were followed for a mean of 9.3 years, including 5.0 years following AFT; control patients were followed for a mean of 8.6 years after primary surgery.

The researchers identified eight locoregional recurrences in the treatment group and 11 among the , for an unadjusted hazard ratio of 0.63 (95 percent confidence interval, 0.25 to 1.60; P = 0.33). In relevant subgroups based on the type of oncologic surgery, tumor invasiveness, or pathologic stage, there were no increased locoregional recurrence rates. With respect to distant recurrences or -specific mortality, no increased risks were detected with AFT.

"In line with reported rates from other published matched cohorts, there is no so far to suggest that AFT leads to increased rates of cancer relapse in with breast cancer," the authors write.


Explore further

'Lipofilling' technique found safe for reconstruction after breast cancer surgery

More information: Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Journal information: JAMA Surgery

Copyright © 2018 HealthDay. All rights reserved.

Citation: Breast cancer recurrence rate not up with autologous fat transfer (2018, November 15) retrieved 22 April 2019 from https://medicalxpress.com/news/2018-11-breast-cancer-recurrence-autologous-fat.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more