Novel scoring system can up access to biologics in psoriasis

Novel scoring system can up access to biologics in psoriasis
(HealthDay)—A new scoring system that accounts for "not relevant" responses (NRRs) on the Dermatology Life Quality Index (DLQI) for patients with psoriasis is valid for avoiding bias and can improve access to biologics, according to a study published in the November issue of the British Journal of Dermatology.

Fanni Rencz, M.D., Ph.D., from Corvinus University of Budapest in Hungary, and colleagues proposed a new scoring system for the DLQI that corrects for the bias in the NRR option (DLQI-R) and examined its construct validity using data from 242 patients (104 of whom marked at least one NRR). For each patient, the DLQI score was calculated according to the original scoring and by applying the new scoring formula. The DLQI-R validity was tested against the Psoriasis Area and Severity Index (PASI) and the three-level five-dimension EuroQoL (EQ-5D-3L).

The researchers found mean scores of 9.99 ± 7.52 and 11.0 ± 8.02 on the DLQI and DLQI-R, respectively. With the DLQI-R , eight more patients (3.3 percent) achieved the "PASI > 10 and DLQI > 10" threshold required by clinical guidelines to become candidates for systemic treatment. When the number of NRRs allowed were limited to two or three, the results were robust. The DLQI-R correlated slightly better with PASI and EQ-5D-3L scores than the DLQI.

"The novel scoring primarily strives to provide fair access to systemic treatments for with ," the authors write.


Explore further

Frontal fibrosing alopecia negatively linked to HRQOL

More information: Abstract/Full Text (subscription or payment may be required)
Editorial
Journal information: British Journal of Dermatology

Copyright © 2018 HealthDay. All rights reserved.

Citation: Novel scoring system can up access to biologics in psoriasis (2018, November 21) retrieved 25 May 2019 from https://medicalxpress.com/news/2018-11-scoring-access-biologics-psoriasis.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
1 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more