Cost burden of disease progression high in multiple myeloma

Cost burden of disease progression high in multiple myeloma

(HealthDay)—The economic burden of disease progression is considerable among multiple myeloma (MM) patients receiving drug therapy across all lines of therapy (LOTs), according to a study published online Aug. 7 in Leukemia & Lymphoma.

May Hagiwara, Ph.D., from Policy Analysis Inc. in Brookline, Massachusetts, and colleagues used data from a large U.S. claims database to examine the effects of disease progression on health care resource utilization (HRU) and costs among patients with MM with one or more LOTs and without receipt of a stem cell transplant. Data were compared for annual HRU and costs in the first four LOTs for patients with and without progression.

The researchers found that patients with versus without progression had greater mean annual hospitalizations and in all LOTs. Among patients with versus without progression, the total incremental annual costs in 1LOT to 4LOTs were $25,920, $30,632, $47,320, and $19,769, respectively.

"For MM patients receiving , the economic burden of disease progression is substantial across all LOTs and this burden is generally greater in the era of novel treatments for relapse and refractory MM," the authors write. "Treatments that delay progression may yield important reductions in downstream disease management ."

One author disclosed financial ties to , including Amgen, which funded the study.

Explore further

Daratumumab cuts risk for progression in multiple myeloma

More information: Abstract/Full Text

Copyright © 2019 HealthDay. All rights reserved.

Citation: Cost burden of disease progression high in multiple myeloma (2019, August 15) retrieved 22 September 2019 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more