Prevention and prognosis of cervical cancer

HPV vaccine
Gardasil vaccine and box. Image: Wikipedia

Jiayao Lei's thesis addresses research questions on prevention and prognosis of cervical cancer within the framework of the interplay of human papillomavirus (HPV), vaccination, and cervical screening, and also provides insights for evidence-based decision-making.

HPV is the major cause of cervical . The well-established from HPV infection to the occurrence of invasive cervical cancer serves as the basis for prevention of cervical cancer through prophylactic HPV vaccination (primary prevention) and (secondary prevention). Cervical cancer detected through screening also has better chances of being cured than cancers not detected through screening.

Jiayao has shown that cervical screening can effectively reduce the risk of adenosquamous cell carcinoma and rare histological types of invasive cervical carcinoma. HPV vaccination can effectively reduce the risk of cervical cancer, which is the ultimate goal of cervical cancer prevention. With the implementation of HPV vaccination, the screening performance of cytology for high-grade cervical lesions has decreased in vaccinated women compared to unvaccinated women, especially among those vaccinated at younger age. Tumor high-risk HPV status is associated with the prognosis of cervical cancer, which could add value to the clinically established prognostic factors.

Jiayao's thesis adds knowledge to the current understanding of cervical cancer prevention strategies and prognosis of cervical cancer, and could potentially serve as a basis for evidence-based decision-making and policy changes in the future.

On March 20, Jiayao will defend her thesis "Prevention and prognosis of : the interplay of human papillomavirus, vaccination and screening."


Explore further

Cervical cancer could be eliminated within a century

More information: Prevention and prognosis of cervical cancer : the interplay of human papillomavirus, vaccination and screening. https://openarchive.ki.se/xmlu … 728851470.1574753981
Citation: Prevention and prognosis of cervical cancer (2020, March 9) retrieved 28 May 2020 from https://medicalxpress.com/news/2020-03-prognosis-cervical-cancer.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
2 shares

Feedback to editors

User comments