Prophylactic antibiotics not needed before invasive dental procedures

Prophylactic antibiotics not needed before invasive dental procedures

(HealthDay)—There is no evidence to support administering antibiotic prophylaxis before invasive dental procedures (IDP) in patients with prosthetic joints, according to a study published online Jan. 19 in JAMA Network Open.

Martin H. Thornhill, M.B.B.S., Ph.D., from University of Sheffield School of Clinical Dentistry in the United Kingdom, and colleagues assessed associations between IDP and subsequent late prosthetic joint infection (LPJI) using data from England, where antibiotic prophylaxis has never been recommended to prevent LPJI. The analysis included 9,427 patients admitted to hospitals in England for LPJI between Dec. 25, 2011, and March 31, 2017.

The researchers found that 25.3 percent had hip prosthetic joints, 33.6 percent had knee prosthetic joints, 2.8 percent had other prosthetic joints, and 38.4 percent had unknown prosthetic joint types. There was no significant temporal association observed between IDP and subsequent LPJI. In fact, there was a lower incidence of IDP observed in the three months prior to LPJI (incidence rate ratio, 0.89).

"These findings refute recommendations to give antibiotic prophylaxis to patients with prosthetic joints prior to IDP, given the cost, adverse drug reaction risk, and potential for promoting associated with ," the authors write.

One author disclosed financial ties to the .


Explore further

Outcomes poorer with six versus 12 weeks of antibiotics for PJI

More information: Abstract/Full Text
Journal information: JAMA Network Open

Copyright © 2021 HealthDay. All rights reserved.

Citation: Prophylactic antibiotics not needed before invasive dental procedures (2022, January 21) retrieved 28 May 2022 from https://medicalxpress.com/news/2022-01-prophylactic-antibiotics-invasive-dental-procedures.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
6 shares

Feedback to editors