Diseases, Conditions, Syndromes

Tracing travelers' typhoid to get an early warning of emerging threats

Salmonella enterica serovar Typhi causes more than 20 million cases of typhoid fever each year, and disproportionately infects children in low and middle income countries. Now, in a paper published in PLOS Neglected Tropical ...

Medical research

Deadly infections on the increase: Urgent need for new antibiotics

Globally, the number of deaths from infections is on the rise as more bacteria become resistant to antibiotics. New classes are desperately needed. A promising resistance inhibitor is now being developed by the research group ...

Medical research

Resistance can spread even without the use of antibiotics

Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore not sufficient to curtail ...

Diseases, Conditions, Syndromes

Multidrug-resistant salmonella outbreak characterized

(HealthDay)—A recent multidrug-resistant (MDR) Salmonella enterica serotype Newport outbreak, affecting patients in 32 states, was associated with soft cheese and beef consumption, according to a report published in the ...

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Antibiotic resistance

Antibiotic resistance is the ability of a microorganism to withstand the effects of antibiotics. It is a specific type of drug resistance. Antibiotic resistance evolves via natural selection acting upon random mutation, but it can also be engineered by applying an evolutionary stress on a population. Once such a gene is generated, bacteria can then transfer the genetic information in a horizontal fashion (between individuals) by plasmid exchange. If a bacterium carries several resistance genes, it is called multiresistant or, informally, a superbug. The term antimicrobial resistance is sometimes used to explicitly encompass organisms other than bacteria.

Antibiotic resistance can also be introduced artificially into a microorganism through transformation protocols. This can aid in implanting artificial genes into the microorganism. If the resistance gene is linked with the gene to be implanted, the antibiotic can be used to kill off organisms that lack the new gene.

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