Significant county-level variability seen with gastrointestinal cancers

Significant county-level variability seen with gastrointestinal cancers

Patient and structural factors contribute to significant geographic differences in mortality from gastrointestinal (GI) cancers, according to a study published in the August issue of Gastroenterology.

Christopher Ma, M.D., M.P.H., from the University of Calgary in Alberta, Canada, and colleagues used data from the U.S. Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research platform (2010 to 2019) to calculate county-level mortality from esophageal, gastric, pancreatic, and .

The researchers observed significant geographic disparities in GI cancer-related county-level mortality across the United States. The ratio of mortality between the 90th and 10th percentile counties ranged from 1.5 for pancreatic to 2.1 for . Counties in the Southeastern United States primarily accounted for the highest 5 percent of mortality rates for gastric, pancreatic, and colorectal cancer. Intercounty variability in mortality rates for esophageal, gastric, pancreatic, and colorectal cancer was partially explained by multivariable models (43, 61, 14, and 39 percent, respectively). GI cancer-related mortality was most strongly associated with cigarette smoking and rural residence (independent of specialist density).

"Our findings support continued public health efforts to reduce smoking use and improve care for rural patients, which may contribute to a reduction in disparities in GI cancer-related death," the authors write.


Explore further

Aspirin use tied to longer bladder, breast cancer survival

More information: Abstract/Full Text
Journal information: Gastroenterology

Copyright © 2022 HealthDay. All rights reserved.

Citation: Significant county-level variability seen with gastrointestinal cancers (2022, July 26) retrieved 24 September 2022 from https://medicalxpress.com/news/2022-07-significant-county-level-variability-gastrointestinal-cancers.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
19 shares

Feedback to editors