This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

reputable news agency

proofread

Febrile urinary tract infections common with neurogenic bladder

Febrile urinary tract infections common with neurogenic bladder

Recurrent febrile urinary tract infections (FUTIs) are common in children with neurogenic bladder, and the risk for rapid progression to chronic kidney disease (CKD) increases in a dose-response manner, according to a study recently published in the European Journal of Pediatric Surgery.

Guanglun Zhou, from Shenzhen Children's Hospital in China, and colleagues evaluated whether , assessed as the estimated glomerular filtration rate, is associated with the number of FUTIs in diagnosed with neurogenic bladder. The analysis included 463 children (mean age, 23 months).

The researchers found that during a median follow-up of 51 months, 302 children had four or more FUTIs and 161 children had none to three FUTIs. From the first to third episodes of FUTI, the incidence of developing CKD grade 3 to 5 gradually increased (1.3 to 2.4 percent) but drastically increased after four episodes (≥22.5 percent), with the incidence reaching 100 percent after eight FUTIs. Compared with children with one FUTI, the odds of CKD grade 3 to 5 in children with four FUTIs were 17.3 and 43.7 times greater after four and six FUTIs, respectively.

"This study showed that recurrent FUTIs are common in children with neurogenic bladder and that the risk of to CKD grade 3 to grade 5 increases substantially after four or more FUTIs," the authors write.

More information: Guanglun Zhou et al, Association of Renal Function (Estimate Glomerular Filtration Rate) with the Number of Febrile Urinary Tract Infections in Children with Neurogenic Bladder, European Journal of Pediatric Surgery (2023). DOI: 10.1055/s-0043-1760823

Copyright © 2023 HealthDay. All rights reserved.

Citation: Febrile urinary tract infections common with neurogenic bladder (2023, March 8) retrieved 22 June 2024 from https://medicalxpress.com/news/2023-03-febrile-urinary-tract-infections-common.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Nomogram predicts upper urinary tract damage in pediatric neurogenic bladder

2 shares

Feedback to editors