This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

peer-reviewed publication

reputable news agency

proofread

Locally recurrent rectal cancer QoL is valid patient-reported outcome measure

Locally recurrent rectal cancer QoL is valid patient-reported outcome measure

A new locally recurrent rectal cancer (LRRC) quality of life (QoL) measure is a valid patient-reported outcome measure (PROM), according to a study published in the May issue of eClinicalMedicine.

Deena P. Harji, M.B.B.S., Ph.D., from the University of Leeds in the United Kingdom, and colleagues developed a disease-specific, psychometrically robust, and validated PROM for use in LRRC. A total of 117 adults in the United Kingdom and Australia with an existing or previously treated LRRC within the last two years completed the proposed LRRC-QoL, European Organisation for Research and Treatment of Cancer Quality of Life-C29 (EORTC QLQ-CR29), and Functional Assessment of Cancer Therapy-Colorectal (FACT-C) questionnaires.

Nine multi-item scales (, , pain, urostomy-related symptoms, lower limb symptoms, stoma, sexual function, sexual interest, and ) and three single items were included in the LRRC-QoL measure.

The researchers found that overall reliability was supported by Cronbach's Alpha and Intraclass correlation values of >0.7 across the majority of scales. Validity was convergent between the LRRC-QoL pain scale and FACT-C Physical Well Being scale; LRRC-QoL psychological impact scale and EORTC QLQ-CR29 Body Image scale and the FACT-C Emotional Well-Being scale; and LRRC-QoL urinary symptoms scale and EORTC QLQ-CR29 Urinary Frequency scale. For gender, disease location, treatment intent, and recurrent disease, known-groups validity was demonstrated.

"The LRRC-QoL has the potential to transform outcome assessment in locally recurrent rectal cancer. In , the LRRC-QoL will be able to quantify patient symptoms, experience, and overall satisfaction," a co-author said in a statement. "This will lead to the disclosure and identification of potential issues not routinely reported and will aid the early detection and subsequent monitoring of symptoms."

More information: Abstract/Full Text

Journal information: EClinicalMedicine

Copyright © 2023 HealthDay. All rights reserved.

Citation: Locally recurrent rectal cancer QoL is valid patient-reported outcome measure (2023, June 12) retrieved 4 March 2024 from https://medicalxpress.com/news/2023-06-locally-recurrent-rectal-cancer-qol.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

New measure of quality of life for patients with locally recurrent rectal cancer

5 shares

Feedback to editors