This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


peer-reviewed publication

reputable news agency


Moderate-to-severe psoriasis tied to lower fertility rates in women

Moderate-to-severe psoriasis tied to lower fertility rates in women

Patients with moderate-to-severe psoriasis have lower fertility rates than women without psoriasis, according to a study published online June 7 in JAMA Dermatology.

Teng-Chou Chen, Ph.D., from the School of Health Sciences at the University of Manchester in the United Kingdom, and colleagues used data from 63,681 with psoriasis and 318,405 matched controls to assess differences in and obstetric outcomes.

The researchers found lower fertility rates (rate ratio, 0.75) among patients with moderate-to-severe psoriasis. Pregnancies in patients with psoriasis had a higher risk for loss (odds ratio, 1.06) compared with pregnancies in matched controls without psoriasis. The two groups were similar with respect to the risks for antenatal hemorrhage, preeclampsia, and .

"In this cohort study, patients with moderate-to-severe psoriasis had a lower fertility rate, and the risk of pregnancy loss was higher than in matched comparators without psoriasis," the authors write. "Future research should identify the mechanism of increased risk of pregnancy loss among patients with psoriasis."

Several authors disclosed financial ties to the .

More information: Teng-Chou Chen et al, Fertility Trends and Adverse Pregnancy Outcomes in Female Patients With Psoriasis in the UK, JAMA Dermatology (2023). DOI: 10.1001/jamadermatol.2023.1400

Journal information: JAMA Dermatology

Copyright © 2023 HealthDay. All rights reserved.

Citation: Moderate-to-severe psoriasis tied to lower fertility rates in women (2023, June 22) retrieved 9 December 2023 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Adverse pregnancy outcomes up for women with psoriasis


Feedback to editors