This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


reputable news agency


Study shows prophylactic low-dose aspirin in pregnancy does not increase IBD activity

ACG: prophylactic low-dose aspirin in pregnancy does not increase IBD activity

Use of low-dose aspirin (LDA) among pregnant women with inflammatory bowel disease (IBD) is not associated with an increased risk for disease activity, according to a study presented at the annual meeting of the American College of Gastroenterology, held from Oct. 20 to 25 in Vancouver, British Columbia, Canada.

Amy Yu, M.D., from the University of California in San Francisco, and colleagues evaluated the prevalence of LDA use in pregnant IBD patients and the effect of LDA on IBD disease activity. The analysis included 325 individuals with IBD and at least one pregnancy followed by a maternal fetal medicine clinic at a tertiary academic medical center from 2013 through 2022.

Of the participants, 29% used LDA. The researchers observed similar cumulative rates of IBD flare during pregnancy or six months postpartum between those who took LDA and those who did not (24 versus 26%). Preterm birth (21 versus 14%), higher parity (two versus one), and cesarean delivery (51 versus 27%) were more likely for individuals on LDA versus those not on LDA.

Cumulative rates of hypertensive disorders of pregnancy were similar between the groups (22 versus 19%), although individuals on LDA had higher rates of preeclampsia (11.6 versus 4.3%). Associations were noted for higher LDA dose (162 mg; odds ratio, 2.77) and diagnosis of ulcerative colitis (UC; odds ratio, 2.34) with flare. When adjusting for LDA dose and prior IBD medication use, diagnosis of UC remained a significant risk factor for flare (odds ratio, 4.49).

"Approximately one-third of patients with IBD cared for in a maternal fetal medicine practice used low-dose aspirin for prevention of hypertensive disorders of pregnancy," Yu said in a statement. "The observed rate of IBD flare during pregnancy or postpartum was not higher in patients who used ."

More information: Press Release, Abstract, More Information

Copyright © 2023 HealthDay. All rights reserved.

Citation: Study shows prophylactic low-dose aspirin in pregnancy does not increase IBD activity (2023, October 27) retrieved 17 April 2024 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Migraine history tied to higher risk for adverse pregnancy outcomes


Feedback to editors