Migraine history tied to higher risk for adverse pregnancy outcomes

Migraine history tied to higher risk for adverse pregnancy outcomes

A self-reported migraine history is associated with a higher risk for some adverse pregnancy outcomes, according to a research letter published online April 30 in the American Journal of Obstetrics & Gynecology.

Eliza C. Miller, M.D., from Columbia University in New York City, and colleagues assessed whether self-reported migraine in nulliparous individuals is associated with higher odds of adverse outcomes. The analysis included 9,450 nulliparous U.S. individuals with singleton gestation in early pregnancy followed through delivery.

The researchers found that 19.1 percent of participants reported a diagnosis of migraine at the first visit. White race, recent smoking history, , and were more common among participants with migraine. In an adjusted analysis, participants with migraine had increased odds of any adverse pregnancy outcome (adjusted odds ratio, 1.26), as well as any hypertensive disorder of pregnancy and both medically indicated and spontaneous preterm birth. A larger effect was seen in participants who reported recent medication use (adjusted odds ratio, 1.49).

"In a diverse, prospective cohort of 9,450 nulliparous U.S. participants, self-reported were associated with 26 percent higher odds of adverse pregnancy outcomes—an effect driven by hypertensive disorders of pregnancy and both medically indicated and spontaneous preterm birth," the authors write. "Migraine may be an underrecognized risk factor for adverse pregnancy outcomes."

More information: Eliza C. Miller et al, Migraine and adverse pregnancy outcomes: the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be, American Journal of Obstetrics and Gynecology (2022). DOI: 10.1016/j.ajog.2022.04.049

© 2022 HealthDay. All rights reserved.

Citation: Migraine history tied to higher risk for adverse pregnancy outcomes (2022, June 3) retrieved 18 May 2024 from https://medicalxpress.com/news/2022-06-migraine-history-tied-higher-adverse.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

No adverse outcomes seen with SARS-CoV-2 vaccination in pregnancy

4 shares

Feedback to editors