Medical research

Probing innate immunity, cGAS protein, and our own damaged DNA

The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling ...

Arthritis & Rheumatism

Is autoimmunity on the rise?

A study published in Arthritis & Rheumatology provides evidence that the prevalence of autoimmunity—when the immune system goes awry and attacks the body itself—has increased in the United States in recent years.

Immunology

Scientists discover new 'Jekyll and Hyde' immune cell

Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with "Jekyll and Hyde properties". These cells play a key protective role in immunity to infection but—if unregulated—also mediate ...

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