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Alcohol use disorder linked to increased odds of suicide mortality

Alcohol use disorder linked to increased odds of suicide mortality

Alcohol use disorder (AUD) is associated with suicide mortality, with a similar association seen across the sexes, according to a review and meta-analysis published online March 12 in JAMA Network Open.

Shannon Lange, M.P.H., Ph.D., from the Center for Addiction and Mental Health in Toronto, and colleagues estimated the sex-specific association between AUD and suicide mortality in a systematic review and meta-analysis. Data were obtained from 24 studies with 37,870,699 participants (23 risk estimates for male and 17 for ).

The researchers found that for both male and female participants, study design (i.e., longitudinal versus cross-sectional) affected the observed association between AUD and suicide mortality (log odds ratios [95 percent confidence intervals], 0.68 [0.08 to 1.28] and 1.41 [0.57 to 2.24], respectively) in sex-specific meta-regression models. Among , the pooled odds ratios (95 percent confidence intervals) were 2.68 (1.86 to 3.87) and 2.39 (1.50 to 3.81) for men and women, respectively.

"Alcohol use disorder is associated with higher odds of death by suicide, an association that is similar across the sexes," the authors write. "It is evident that identifying and treating AUD is an important component of a comprehensive suicide prevention strategy."

More information: Shannon Lange et al, Sex-Specific Association of Alcohol Use Disorder With Suicide Mortality, JAMA Network Open (2024). DOI: 10.1001/jamanetworkopen.2024.1941

Journal information: JAMA Network Open

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Citation: Alcohol use disorder linked to increased odds of suicide mortality (2024, March 13) retrieved 23 May 2024 from https://medicalxpress.com/news/2024-03-alcohol-disorder-linked-odds-suicide.html
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