This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

fact-checked

reputable news agency

proofread

Vitamin D deficiency tied to worse outcomes with early kidney disease

Vitamin D deficiency tied to worse outcomes with early kidney disease

Vitamin D deficiency is associated with increased risks for cardiovascular mortality and chronic kidney disease (CKD) progression in patients with early-stage disease, according to a study published online May 11 in the Journal of Endocrinological Investigation.

Yanhong Lin, from Southern Medical University in Guangzhou, China, and colleagues examined the effects of 25-hydroxyvitamin D (25[OH]D) deficiency on cardiovascular mortality and kidney outcomes in patients with early-stage CKD. The analysis included 9,229 adult patients with CKD (stages 1 to 3) from 19 medical centers across China (January 2000 to May 2021).

The researchers found that compared with patients having 25(OH)Dā€‰ā‰„20 ng/mL, a there was a significantly higher risk for (hazard ratio, 1.90) and CKD progression (hazard ratio, 2.20) as well as a steeper annual decline in estimated (estimate, āˆ’7.87 percent per year) in those with serum 25(OH)Dā€‰<10 ng/mL.

"In conclusion, 25(OH)D deficiency was common in patients with early-stage CKD," the authors write. "Vitamin D status should be closely monitored in patients with early CKD. Well-designed randomized clinical trials are needed to determine whether timely vitamin D supplementation can prevent cardiovascular events and loss of kidney function in patients with early-stage CKD and 25(OH)D deficiency."

More information: Y. Lin et al, Association of serum 25-hydroxyvitamin D with cardiovascular mortality and kidney outcome in patients with early stages of CKD, Journal of Endocrinological Investigation (2024). DOI: 10.1007/s40618-024-02383-6

Copyright © 2024 HealthDay. All rights reserved.

Citation: Vitamin D deficiency tied to worse outcomes with early kidney disease (2024, May 20) retrieved 15 June 2024 from https://medicalxpress.com/news/2024-05-vitamin-d-deficiency-worse-outcomes.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

High systemic immune-inflammation index tied to higher mortality with peritoneal dialysis

0 shares

Feedback to editors