This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


reputable news agency


Researchers say multimodal antiobesity medications yield superior preoperative weight loss

Multimodal antiobesity medications yield superior preoperative weight loss

Combining antiobesity medications enhances preoperative weight loss in individuals with high body mass index (BMI) preparing for metabolic surgery, according to a study presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery, held from June 9 to 13 in San Diego.

Michael Kachmar, D.O., from the Pennington Biomedical Research Center in Baton Rouge, Louisiana, and colleagues characterized the success of preoperative weight-loss therapy among patients with high BMI (≥70 kg/m2) preparing for . The analysis included 113 patients.

The researchers found that length of treatment ranged from 2.7 to 364 weeks, with an average time of 72.9 days. For nonpharmacologic medically supervised weight loss, the mean percent total body weight loss (%TBWL) was 5.95%; %TBWL was 8.14% for mono-glucagon-like peptide 1 and 13.1% for multimodal antiobesity medication. Mean absolute BMI reductions were 7.36, 7.51, and 9.61 kg/m2, respectively.

Both %TBWL and absolute BMI reduction were highest for those treated with multimodal antiobesity medication therapy for 23 to 51 weeks.

"Combining antiobesity medications may achieve much greater presurgery weight loss than other methods for those with extreme obesity," co-author Phil Schauer, M.D., also from Pennington Biomedical, said in a statement. "Many patients who would otherwise be considered 'too sick for surgery' may now qualify."

More information: Press Release

Annual Meeting Information

Copyright © 2024 HealthDay. All rights reserved.

Citation: Researchers say multimodal antiobesity medications yield superior preoperative weight loss (2024, June 18) retrieved 19 July 2024 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Pre-operative use of GLP-1s may reduce complications after metabolic, bariatric surgery in patients with extreme obesity


Feedback to editors