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Parkinson's & Movement disorders news
Parkinson's & Movement disorders
AI-driven MRI analysis improves accuracy in distinguishing Parkinsonian disorders
University of Florida researchers have led a multicenter study demonstrating that Automated Imaging Differentiation for Parkinsonism (AIDP), a machine-learning method using magnetic resonance imaging (MRI), accurately distinguishes ...
14 hours ago
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Neuroscience
Refined test could improve Parkinson's disease diagnosis
A team that includes a RIKEN researcher has refined a lab test for measuring protein aggregate levels in samples from patients with certain neurodegenerative diseases. This has the potential to improve diagnosis and drug ...
14 hours ago
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Treatment for Parkinson's disease and restless leg syndrome is linked with risky behavior
Getting a headache and feeling sick are common side-effects for many medicines. Indulging in risky sexual behavior or pathological gambling—not so common.
Mar 17, 2025
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Scientists solve decades-long Parkinson's mystery
WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for the development of new drugs to treat the condition.
Mar 13, 2025
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ITSN1 gene linked to substantial risk of Parkinson's disease
A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a significantly elevated risk of Parkinson's disease, a neurodegenerative condition that affects nearly ...
Mar 7, 2025
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Cases of Parkinson's disease set to reach 25 million worldwide by 2050, study suggests
By 2050, there will be 25.2 million people living with Parkinson's disease worldwide (a 112% increase from 2021), largely due to population aging, suggests a modeling study published by The BMJ.
Mar 5, 2025
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Understanding how metabolism contributes to Parkinson's disease
Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's disease, according to a study published in Nature Communications.
Mar 4, 2025
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Sleep apnea linked to increased risk of Parkinson's: Study suggests CPAP may reduce risk
People with obstructive sleep apnea have an increased risk of Parkinson's disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study presented at ...
Mar 2, 2025
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Blood test could lead to better diagnosis and management of ALS
ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ...
Feb 26, 2025
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Men's immune response to brain protein may explain their higher rates of Parkinson's disease
Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease. Their new research reveals how a protein in brain cells may drive Parkinson's onset—and offers a ...
Feb 25, 2025
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Studies of Parkinson's disease have long overlooked Pacific populations—meta-analysis shows why that must change
A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.
Feb 25, 2025
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Platform trials streamline ALS therapy evaluation by rapidly ruling out ineffective drugs
Massachusetts General Hospital coordinated the first four platform trials within the HEALEY ALS platform to evaluate potential treatments for amyotrophic lateral sclerosis (ALS), with results published in various JAMA journals.
Study: Socioeconomic factors, unpredictability complicate diagnosis of episodic disabilities, like epilepsy
Any patient suffering from new or worsening medical symptoms hopes for a relatively quick and accurate diagnosis.
Feb 19, 2025
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Cholesterol metabolism byproduct linked to Parkinson's disease
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the ...
Feb 18, 2025
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Study of familial ALS in Egypt reveals that genetic variations may contribute to disease progression
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death. While significant strides have ...
Feb 18, 2025
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Novel antibody discovery platform may inform Alzheimer's and Parkinson's research
In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and ...
Feb 17, 2025
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Global study identifies markers for the five clinical stages of Parkinson's disease
From a study that analyzed brain images of more than 2,500 people with Parkinson's disease in 20 different countries, scientists have been able to identify patterns of neurodegeneration and create metrics for each of the ...
Feb 12, 2025
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From fingers to toes, wearable and vibrating technology could help Parkinson's patients
Fingernail-sized vibrating gadgets, similar to the tiny devices that make your cellphone buzz, could help people with Parkinson's disease navigate the world with more confidence and ease. The vibrating devices, which may ...
Feb 12, 2025
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New research uncovers brain changes in Parkinson's disease
Researchers at Karolinska Institutet have discovered new insights into brain changes in Parkinson's disease using advanced imaging techniques.
Feb 12, 2025
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New study reveals how DNA repair genes play a major role in Huntington's disease
A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream ...
Feb 11, 2025
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FDA approves wearable infusion device for advanced Parkinson disease
The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced ...
Feb 6, 2025
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The link between renal failure and Parkinson's disease: Researchers illuminate the underlying mechanisms
Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the protein α-synuclein in nerve cells. When misfolded, this protein can produce clumps known as Lewy ...
GLP-1 drug shows little benefit for people with Parkinson's disease, trial finds
The GLP-1 drug, exenatide, has no positive impact on the movement, symptoms or brain imaging of people with Parkinson's, finds a new study led by UCL researchers.
Feb 4, 2025
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Compound with neuroprotective properties shows promise for Parkinson's treatment
A compound that showed early promise in the treatment of Parkinson's disease in fruit flies has also shown neuroprotective effects in mice, according to researchers at The University of Alabama.
Feb 3, 2025
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Q&A: How a scientist helped ban a chemical connected to Parkinson's disease
The U.S. will ban nearly all uses of the common industrial cleaning agent, trichloroethylene (TCE), this year—more than 50 years after it led to one of the country's worst cases of contaminated drinking water. It has been ...
Jan 30, 2025
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