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Parkinson's & Movement disorders news
Parkinson's & Movement disorders
Medications that suppress REM sleep improve survival in amyotrophic lateral sclerosis patients
During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases. Now new research published at the ATS 2025 International Conference has shown ...
21 hours ago
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Neuroscience
CRISPR study reveals mitochondrial dysfunction as early marker in amyotrophic lateral sclerosis
Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common denominator for different gene ...
May 20, 2025
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Protein complex discovery may unlock DNA repair mechanism in Huntington's disease
Huntington's disease is a genetic disorder that kills nerve cells in the brain, causing people to lose their cognitive and motor abilities. New research led by Thomas Jefferson University researcher Anna Pluciennik, Ph.D. ...
May 20, 2025
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Treatment design software personalizes medicine plans for people with movement impairments
Impaired neuromusculoskeletal function due to conditions such as stroke, osteoarthritis, cerebral palsy, Parkinson's disease, limb amputation, spinal cord injury, traumatic brain injury and cancer is a leading cause of disability ...
May 20, 2025
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Researchers pinpoint 'sweet spot' for focused ultrasound to provide essential tremor relief
For millions of people around the world with essential tremor, everyday activities from eating and drinking to dressing and doing basic tasks can become impossible. This common neurological movement disorder causes uncontrollable ...
May 14, 2025
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High hopes and high costs: Exploring advances in Duchenne muscular dystrophy gene therapy
To help neurologists, clinicians and families understand the current evidence for a new gene therapy for Duchenne muscular dystrophy called delandistrogene moxeparvovec, the American Academy of Neurology (AAN) has issued ...
May 14, 2025
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Golf course proximity linked to higher Parkinson's disease risk
Barrow Neurological Institute and Mayo Clinic-led researchers report an association between living near golf courses and increased Parkinson's disease (PD) risk in a study published in JAMA Network Open.
Low-dose interleukin-2 added to standard ALS treatment extends patient survival, clinical trial finds
The results of the MIROCALS randomized clinical trial have shown that adding low-dose interleukin-2 (IL2LD) to standard treatment for amyotrophic lateral sclerosis slowed functional decline and extended the lifespan of people ...
May 13, 2025
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ALS drug testing in patient-derived cells provides personalized window into nervous system
Unlike other pathologies, amyotrophic lateral sclerosis (ALS) cannot be reproduced accurately in animal models, complicating the development of effective drugs. Faced with this challenge, a group of researchers from IMDEA ...
May 13, 2025
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Cell death discovery could lead to next-gen drugs for neurodegenerative conditions
Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team at WEHI, including researchers from the Parkinson's ...
May 12, 2025
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New study highlights potential of digital mental health intervention for people with Parkinson's
Digital mental health interventions can effectively improve the well-being of people with Parkinson's, according to a new study led by researchers at City St George's, University of London.
May 12, 2025
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Simple brain scan offers hope for detecting Parkinson's disease much earlier
An international team, led by researchers at the Champalimaud Foundation (CF), has shown—for the first time in a realistic way—that it may be possible to diagnose Parkinson's disease (PD) years before it becomes untreatable, ...
May 8, 2025
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Exercise enhances stem cell transplant function in Parkinson's disease, study finds
Parkinson's disease (PD) is a disabling neurodegenerative disease that affects approximately 10 million people worldwide, with numbers steadily increasing. Symptoms include tremors, difficulties with movement and speech, ...
May 8, 2025
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Eating ultra-processed foods may speed up early signs of Parkinson's disease
People who eat more ultra-processed foods like cold breakfast cereal, cookies and hot dogs are more likely to have early signs of Parkinson's disease when compared to those who eat very few ultra-processed foods, according ...
May 7, 2025
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Promising Parkinson's drug decoded
How well our brain functions depends heavily on the performance of our nerve cells. That is why they are regularly checked for their proper function—defective cell components are marked, disposed of and recycled. This includes ...
May 5, 2025
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Science supports exercise as medicine: Patients with Parkinson's see benefits
At 79, Sarah Schoentgen exercises more than many people half her age. On top of walking in her Denver neighborhood and pedaling on her home stationary bike, Schoentgen works out at least twice weekly with a personal trainer ...
May 5, 2025
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What you should know about ALS, also known as Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS)—known as Lou Gehrig's Disease, based on the iconic 1930s New York Yankee baseball player—is a progressive neurodegenerative disease that affects thousands of Americans every year. ALS ...
May 5, 2025
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Editing Parkinson's disease—discovery of an inflammatory RNA editing enzyme
Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage. Through international collaboration, researchers at KAIST have ...
May 2, 2025
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Detecting Parkinson's disease with a simple retinal exam
Could it be possible to diagnose Parkinson's disease with the help of a simple retinal exam? The idea should be seriously considered, according to a study published in the May issue of Neurobiology of Disease by researchers ...
May 1, 2025
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Existing treatments may help fight symptoms of severe form of muscular dystrophy
A new study led by researchers at the Hospital for Special Surgery (HSS) suggests that currently available therapies may help control chronic muscle inflammation in Duchenne muscular dystrophy (DMD), a severe condition that ...
Apr 30, 2025
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Research on α-synuclein PET imaging illuminates path to earlier diagnosis of Parkinson's disease
In an article published in Genomic Psychiatry, researchers from Fudan University and Shanghai University of Traditional Chinese Medicine highlight remarkable advances in the development of positron emission tomography (PET) ...
Apr 30, 2025
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First 'smart,' wearable, pediatric soft exoskeleton provides mobility for children with motor difficulties
Just one look at the next-generation lightweight, soft exoskeleton for children with cerebral palsy reveals the powerful role technology can play in solving global challenges and improving lives.
Apr 29, 2025
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'Magic mushrooms' show promise for improving motor function and mood in Parkinson's patients
Psilocybin, a natural compound found in certain mushrooms, has shown promise in treating depression and anxiety. UC San Francisco researchers wanted to know if it could be used to help Parkinson's patients who often experience ...
Apr 29, 2025
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New insight into how the brain switches gears could help Parkinson's patients
New USC research offers an unseen insight into how the brain shifts gears. The researchers have discovered that our innate ability to make quick changes in motor function is the result of a unique brain mechanism.
Apr 28, 2025
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Spinal fluid biomarker offers early and accurate Parkinson's disease diagnosis
Parkinson's disease is a neurodegenerative disorder that is usually diagnosed in its late stage on the basis of clinical symptoms, mainly motor disorders. By this point, however, the brain is already severely and irreparably ...
Apr 25, 2025
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