Genetics
Unlocking a secret of stem cell stability
Proper embryonic development depends on a signaling pathway that helps to preserve stem cell "immaturity."
Nov 6, 2013
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Agency for Science, Technology and Research (A*STAR), Singapore
Genetics
Scientists identify mutation that causes skin hyperproliferation
Scientists have identified a mutation in a gene that causes patches of very thick skin to appear on the palms and soles of affected people. This skin disorder is related, albeit in a much milder form, to that of the Indonesian ...
Oct 18, 2012
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Oncology & Cancer
A deeper understanding of chromosome capping could improve therapies for both cancer and aging
Switching off the enzyme that adds protective caps to chromosome ends could help fight many types of cancer, A*STAR researchers have shown. The team demonstrated the treatment's potential by using it to thwart tumor growth ...
Dec 20, 2018
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Cardiology
A tool for isolating progenitor cells from human heart tissue could lead to heart repair
A*STAR researchers and colleagues have developed a method to isolate and expand human heart stem cells, also known as cardiac progenitor cells, which could have great potential for repairing injured heart tissue.
Oct 7, 2015
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Medical research
Photoacoustic and magnetic resonance imaging visualizes blood flow and oxygenation status in brain tumor tissue
Cancer diagnostics and therapy monitoring have moved into a new dimension through A*STAR research, which has developed a high-resolution and noninvasive approach to visualize brain tumors by combining photoacoustic with magnetic ...
Jul 20, 2016
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Medications
Thermal stress elicits genomic changes that can make cancer cells resistant to chemotherapy
Harsh treatments that fail to eliminate tumors can make them more resilient, a new A*STAR study finds. Elevated temperature, nutrient deprivation, or other environmental stressors can cause cancer cells to acquire large-scale ...
Feb 22, 2019
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Biomedical technology
A novel protein therapy for efficient skin wound healing
A protein named Agrin has been discovered to promote wound healing and repair, when it is triggered after skin tissue is injured. These findings could pave the way for the development of Agrin protein therapy to accelerate ...
Dec 6, 2021
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Overweight & Obesity
Father's weight is just as relevant as the mother's in determining a child's risk of obesity
It's not only women who should be concerned about the impact of their weight on their children's health. A*STAR researchers have identified a set of factors, including the father's weight, that combine to increase a child's ...
Nov 16, 2017
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Genetics
A master gene determines whether cells become pancreatic or liver cells
A gene in human embryonic stem cells not only steers them to form a pancreas but simultaneously prevents them from becoming liver cells, A*STAR researchers have shown. This discovery is an important step toward growing functioning ...
Jul 15, 2015
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Diseases, Conditions, Syndromes
A small molecule outclasses larger ones in combating drug-resistant bacteria that cause skin infections
A promising drug candidate to address the growing problem of antibiotic-resistant skin infections has been discovered by A*STAR researchers.
Apr 6, 2016
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