Agency for Science, Technology and Research (A*STAR), Singapore

Medical research

The dark side of antibiotics and what we can do about it

As early as the 13th century, scholars proposed that diseases were caused by 'invisible entities' unseen to the naked eye. However, it was not until the 1670s when Antonie van Leeuwenhoek made his microscope did the theory ...

Neuroscience

Q&A: Dissecting movement disorders through the eyes of a fly

Every time we move, electrical impulses are channeled along neuronal highways, jumping from nerve cell to nerve cell until they reach a muscle, causing it to contract. Because muscle movement depends on neuronal function, ...

Medical research

A promising therapeutic modality against the coronavirus

Since the emergence of the novel coronavirus in late 2019, multiple approaches for treating COVID-19 have been considered, from the use of repurposed medicines such as the antimalarial drug, hydroxychloroquine, to the Ebola ...

Medical research

Identifying antibodies that work

A new test manufactured by A*STAR's Diagnostics Development Hub in partnership with Duke-NUS Medical School could reveal if an individual is likely immune to COVID-19.

Diseases, Conditions, Syndromes

The mutation making SARS-CoV-2 milder

Like any other organism on the planet, the SARS-CoV-2 virus is prone to the natural genetic diversity that may arise from mutations. Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hit the world, there ...

Medical research

The fast track to a 'Fortitude Kit' for rapid COVID-19 diagnosis

It may seem like a lifetime ago, but it was only in late January 2020 that Singapore confirmed its first case of the then-novel coronavirus causing COVID-19. Amid the frenzied atmosphere of the Chinese New Year holidays, ...

Diseases, Conditions, Syndromes

What we know about COVID-19 and how it can be treated

When my team and I first learned about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 2019 (COVID-19), we sprang into action, searching the literature to identify the gaps. In times of ...

Diabetes

Weaponizing stem cells in the war on diabetes

There's no sugar coating it—diabetes is shaping up to become one of the greatest health challenges in modern times. According to the World Health Organization (WHO), one in eleven individuals suffers from diabetes, and ...

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