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Oncology & Cancer

Tumor cells' drug addiction may be their downfall

Blocking the processes that drive cancer cell growth is at the heart of many new anti-cancer therapies. Unfortunately, after initial success, cancer cells are generally able to develop workarounds to reactivate the pathways ...

Obstetrics & gynaecology

Older wombs linked to complications in pregnant mice

Deciding to start a family later in life could be about more than just the age of your eggs. A new study in mice suggests the age of a mother's womb may also have a part to play. This work, led by Dr Myriam Hemberger at the ...

Genetics

Kick-starting the genome in early development

After the fertilisation of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, ...

Oncology & Cancer

Fundamental research enhances understanding of major cancer gene

New research represents a promising step towards better understanding of a key cancer gene. A long-running collaboration between researchers at the Babraham Institute, Cambridge and the AstraZeneca IMED Biotech Unit reveals ...

Medical research

Single-cell technique could provide 'egg health' indicators

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to ...

Medical research

Phat on potential, lipidomics is gaining weight

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time. For the past 15 years, scientists have been working to specify and classify these fatty acids ...

Genetics

Mapping genes could improve cancer diagnosis

Large-scale changes to the structure of the genome are often seen in cancer cells. Scientists at the Babraham Institute in Cambridge, UK, have found a way to detect these changes, which could enhance cancer diagnosis and ...

Medical research

Movement of mTORC1 observed for the first time in live cells

What do proteins and wild bears have in common? Just like tagging wild animals aims to allow researchers to observe and track their natural behaviour, molecular researchers use tags to track the minute movements of proteins ...

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