The Broad Institute is a genomic medicine research center located in Cambridge, Massachusetts, United States. Although it is independently governed and supported as a 501(c)(3) nonprofit research organization, the institute is formally affiliated with the Massachusetts Institute of Technology, Harvard University and its affiliated hospitals. The faculty and staff of the Broad Institute include physicians, geneticists, and molecular, chemical, and computational biologists.
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Our bodies burn carbohydrates, proteins, and fat for fuel, and now, researchers at the Broad Institute of MIT and Harvard and the University of Lausanne have discovered another important energy source for cells: uridine, ...
May 18, 2023
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New research suggests that centenarians—people who live to be at least 100—have a diverse collection of viruses in their gut that could help protect them from infectious diseases. The findings, published May 15 in Nature ...
May 16, 2023
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Although bipolar disorder and schizophrenia are diagnosed as distinct psychiatric conditions, both are considerably heritable with molecular roots that are poorly understood. Some people diagnosed with one disorder have symptoms ...
May 12, 2023
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To get an inside look at the heart, cardiologists often use electrocardiograms (ECGs) to trace its electrical activity and magnetic resonance images (MRIs) to map its structure. Because the two types of data reveal different ...
May 1, 2023
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A team of researchers at the Broad Institute of MIT and Harvard has developed a new approach to next-generation sequencing that detects genetic mutations within single molecules of DNA.
Apr 28, 2023
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For patients with some types of cancer, diagnosis can happen at an advanced stage. While a tumor grows unnoticed, it accumulates hundreds to thousands of mutations, making it difficult for scientists studying late-stage cancers ...
Apr 21, 2023
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Researchers have developed a technology, FALCON, to analyze the effects of free fatty acids in any cell type, and found type 2 diabetes genes that may further boost diabetes risk when cells are in a high-fat environment.
Apr 19, 2023
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One of the newest types of cancer drugs, immunotherapies called immune checkpoint inhibitors, has transformed the treatment of lung cancer over the last decade—dramatically improving the survival of some patients with the ...
Apr 19, 2023
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Second only to the notorious TP53 gene, the genes for assemblages known as mSWI/SNF protein complexes are the most frequently mutated entities in cancer cells. Made up of 10 to 15 subunits, the complexes are built from the ...
Apr 10, 2023
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Much of the research on new cancer treatments in the last two decades has focused on genetic targets that allow cancers to grow and spread by altering cell signaling or shutting off tumor suppressors. There is a growing body ...
Apr 7, 2023
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