Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that ...
Jun 15, 2017
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Researchers have uncovered how mutations in a protein network drive several high-risk leukemias, offering new prospects for novel therapies. An existing drug might be repurposed to treat these leukemias, and the new understanding ...
Jun 14, 2017
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Patients who undergo the Fontan operation as children for a complex congenital heart defect are at risk of developing progressive liver fibrosis, a buildup of fibrous deposits, as a result of the circulation created by the ...
May 31, 2017
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Adolescent males of color treated for violent injury and discharged from an urban pediatric emergency department (ED) overwhelmingly identified a need for mental health care, according to research from Children's Hospital ...
May 16, 2017
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Researchers investigating a form of adult-onset diabetes that shares features with the two better-known types of diabetes have discovered genetic influences that may offer clues to more accurate diagnosis and treatment.
May 4, 2017
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As children with single-ventricle disease, a complex and severe heart defect, undergo a series of three reconstructive surgeries, pediatric researchers have detected higher rates of brain abnormalities at each stage. The ...
May 3, 2017
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A unique womb-like environment designed by pediatric researchers could transform care for extremely premature babies, by mimicking the prenatal fluid-filled environment to give the tiniest newborns a precious few weeks to ...
Apr 25, 2017
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A new study from Children's Hospital of Philadelphia (CHOP) finds one in three adolescents with autism spectrum disorder (ASD) acquires an intermediate driver's license, and the majority does so in their 17th year. The vast ...
Apr 11, 2017
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When is it appropriate to treat short children with growth hormone? The answer is not always clear-cut, as many parents and physicians have discovered over the past three decades.
Jan 25, 2017
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Critically ill infants and children do not gain extra benefit from control of their blood sugar level to lower levels, compared to higher levels within the usual care range, say researchers who led a national clinical trial. ...
Jan 25, 2017
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