Scientists have discovered that a receptor on the surface of brain cells plays a key role in regulating how both animals and people respond to stress. The research suggests that the receptor may represent an important biomarker ...
Sep 4, 2019
0
940
Building on a track record of developing adeno-associated viral (AAV) vectors as a groundbreaking clinical tool for gene therapy and gene editing, Children's Hospital of Philadelphia (CHOP) researchers report a more sensitive ...
Jul 30, 2019
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82
Faced with a preteen boy in pain and struggling to breathe from a severe, deteriorating rare condition, researchers at Children's Hospital of Philadelphia identified the responsible gene mutation and harnessed that knowledge ...
Jul 1, 2019
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0
A team of researchers at Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) discovered a new gene associated with severe childhood epilepsy using a novel computational ...
May 16, 2019
0
18
Scientists have shown that transplanting gut bacteria, from an animal that is vulnerable to social stress to a non-stressed animal, can cause vulnerable behavior in the recipient. The research reveals details of biological ...
May 7, 2019
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2449
Using CRISPR gene editing, a team from Children's Hospital of Philadelphia (CHOP) and Penn Medicine have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours after birth. ...
Apr 17, 2019
3
43
Biomedical researchers plan to create the Pediatric Cell Atlas (PCA), a powerful new resource for fine-grained scientific understanding of human growth and development. Drawing on dramatic recent advances in technology, the ...
Mar 28, 2019
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27
Scientists have harnessed powerful data analysis tools and three-dimensional studies of genomic geography to implicate new risk genes for osteoporosis, the chronic bone-weakening condition that affects millions of people. ...
Mar 21, 2019
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21
A new map of newborn babies' brains offers details of structure that will provide a new reference for researchers studying both typical brain development and neurological disorders. Using noninvasive, 20-minute magnetic resonance ...
Feb 18, 2019
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167
Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. A new study found that when a nuclear ...
Sep 11, 2018
0
96
