A research group led by Prof. Du Xuemin from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has developed a "smart" contact lens that can show real-time changes in moisture and pressure ...
Feb 19, 2020
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Tumor cells are characterized by high degree of heterogeneity and among them, tumor-initiating cells (TICs), sometimes also called cancer stem-like cells, are considered as the culprits of cancer development and progression, ...
Feb 17, 2020
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Inflammatory bowel disease (IBD) is a category of refractory inflammatory disease, of which ulcerative colitis (UC) and Crohn's disease (CD) are the main types.
Jan 21, 2020
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Recent evidence suggests a link between cholesterol metabolism and innate immunity. Upon viral infection, macrophages show reduced cholesterol synthesis accompanied by enhanced expression of antiviral genes, including type ...
Dec 27, 2019
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Sarcomas—cancers that arise from transformed mesenchymal cells (a type of connective tissue)—are quite deadly. Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma and are initiated by activating ...
Oct 24, 2019
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Despite the remarkable success of molecular targeted therapy in recent years, the rapid increase of drug resistance is a major obstacle to effective treatment of lung cancer.
Jul 9, 2019
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The dentate gyrus (DG) is the input region of the hippocampus and plays an important role in learning and memory. Although emerging evidence suggests that abnormal expression of the polycomb repressive complex 2 protein (PRC2) ...
Jun 14, 2019
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As early responders in the surveillance of malignant cells, natural killer (NK) cells play a significant role in the control of transformed cells at the tumor initiation stage through direct cytolysis. For this reason, NK ...
May 30, 2019
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Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing the exons of thousands of genes in eukaryotes. They are generally expressed at low levels and often exhibit cell-type-specific and tissue-specific ...
Apr 26, 2019
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Researchers from the Institute of Neuroscience and their collaborators have revealed a new cellular mechanism for amyotrophic lateral sclerosis (ALS), suggesting a novel therapeutic strategy targeting the RNA degradation ...
Apr 9, 2019
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