Cold Spring Harbor Laboratory

Cold Spring Harbor Laboratory, (CSHL) traces its roots to 1890. It is presently located in Suffolk County, Long Island, New York. The private, not for profit lab scientists from the Carnegie Institution of Department of Genetics have made significant contributions in the study and treatment of genetics and medicine. Recently, The Watson School of Biological Sciences was established which employs 400 scientists. CSHL has an educational and research component. CSHL has eight Nobel Laureates who have been associated with the lab. Many break-through discoveries have been made at CSHL. Among the discoveries is the work by John D. Watson who co-discovered the double helix structure of DNA with Francis Crick. Robert J. Roberts received the Nobel Prize for the co-discovery of introns and RNA splicing. CSHL requires all inquiries from the media and public go through Mr. Tarr, e-mail provided.

One Bungtown Road Cold Spring Harbor, NY 11724 516-367-8800

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Researchers discover how hormones define brain sex differences

Sex hormones play an important role in shaping an animal's behavior, and their influence starts early. Early-life hormonal surges help shape the developing brain, establishing circuitry that will influence behavior for a ...

Oncology & Cancer

Paving a path to triple-negative breast cancer treatment

It's the cancer version of "mini me." Cold Spring Harbor Laboratory (CSHL) Professor David Spector, among others, has developed organoids, which are miniature, three-dimensional copies of cancers. Organoids can be derived ...


Maternal protective behaviors run deep

The image of a mouse mom fetching her pup safely home calls to mind a human mother's rapid response when their toddler wanders toward danger. Neuroscientists at Cold Spring Harbor Laboratory (CSHL) now report this resemblance ...


Uncovering how immune cells nurture brain connections

Microglia, the immune cells of the brain, are known for eating up unwanted items like germs and debris, much as their counterparts do in the rest of the body. In early childhood, certain microglia remove unneeded connections, ...

Oncology & Cancer

Pushing past pancreatic tumors' defenses

Our immune systems have the potential to find and destroy cancer cells. But cancer cells can be clever and develop tricks to evade the immune system. Cold Spring Harbor Laboratory Professor Douglas Fearon and his former ...

Diseases, Conditions, Syndromes

Drug halts immune reactions to save damaged lungs

A team of scientists led by Cold Spring Harbor Laboratory (CSHL) have discovered that disulfiram, an FDA-approved drug, prevents the immune system from producing toxic webs known as neutrophil extracellular traps (NETs). ...

Oncology & Cancer

Cutting off liver cancer's nutrient supply chain

The World Health Organization projects that starting in 2030, over a million people will die each year from liver cancer. Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer, former postdoc Wai Kit Ma, and Dillon ...


Finding structure in the brain's static

While sleeping, the entire brain rolls through long, slow waves of electrical activity, like waves on a calm ocean. Researchers call that state of consciousness "slow wave sleep." Waking up changes the pattern of electrical ...


Editing RNA to fix protein problems in cystic fibrosis

The process of generating proteins from genes is akin to a factory, where workers follow a set of instructions that, ideally, are effective and clear. But for some people who suffer from cystic fibrosis (CF), one of their ...

Oncology & Cancer

Obscure protein is spotlighted in fight against leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it. Cold Spring Harbor Laboratory (CSHL) Professor Christopher Vakoc and former graduate student ...

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