Cold Spring Harbor Laboratory

Cold Spring Harbor Laboratory, (CSHL) traces its roots to 1890. It is presently located in Suffolk County, Long Island, New York. The private, not for profit lab scientists from the Carnegie Institution of Department of Genetics have made significant contributions in the study and treatment of genetics and medicine. Recently, The Watson School of Biological Sciences was established which employs 400 scientists. CSHL has an educational and research component. CSHL has eight Nobel Laureates who have been associated with the lab. Many break-through discoveries have been made at CSHL. Among the discoveries is the work by John D. Watson who co-discovered the double helix structure of DNA with Francis Crick. Robert J. Roberts received the Nobel Prize for the co-discovery of introns and RNA splicing. CSHL requires all inquiries from the media and public go through Mr. Tarr, e-mail provided.

Address
One Bungtown Road Cold Spring Harbor, NY 11724 516-367-8800
Website
http://www.cshl.edu/index.html
Wikipedia
http://en.wikipedia.org/wiki/Cold_Spring_Harbor_Laboratory

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Medical research

The first mouse model of human pancreas cancer subtypes

Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help ...

Oncology & Cancer

How breast cancer cells sneak past local immune defenses

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...

Genetics

How to map brain connections using DNA barcodes

A new method developed at Cold Spring Harbor Laboratory (CSHL) uses DNA sequencing to efficiently map long-range connections between different regions of the brain. The approach dramatically reduces the cost of mapping brain-wide ...

Neuroscience

How chandelier cells light up the brain

Within the intricate network of cells that make up the brain, chandelier cells stand out for their elaborate, branching structure. With an elegant shape similar to that of its namesake, a single chandelier cell reaches out ...

Oncology & Cancer

Pregnancy reprograms breast cells, reducing cancer risk

An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the ...

Oncology & Cancer

Why pancreatic ductal adenocarcinoma is so lethal

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire ...

Oncology & Cancer

Extra chromosomes in cancers can be good or bad

Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes. A missing or extra copy of a single chromosome creates an imbalance ...

Oncology & Cancer

Mutation's role in blood cancers revealed by ideal team-up

A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers. Thanks to a collaboration between biologists at Cold Spring Harbor Laboratory (CSHL) and an ...

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