European Molecular Biology Laboratory

Genetics

Genomic sequencing aids the global tuberculosis fight

The COVID-19 pandemic continues, but there is another global infectious disease that has a huge impact on the world. Tuberculosis (TB) causes over 1.5 million deaths and over 10 million infections per year. Estimates suggest ...

Medications

The impact of drugs on gut microbes is greater than we thought

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute ...

Medications

Tackling the collateral damage from antibiotics

Antibiotics cure bacterial infections and save millions of lives each year. But they can also harm the helpful microbes residing in the gut, weakening one of the body's first lines of defense against pathogens and compromising ...

Diseases, Conditions, Syndromes

SARS-CoV-2 curtails immune response in the gut

In an effort to determine the potential for COVID-19 to begin in a person's gut, and to better understand how human cells respond to SARS-CoV-2, scientists at the European Molecular Biology Laboratory used human intestinal ...

HIV & AIDS

A new piece of the HIV infection puzzle explored

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell. The electron tomographic ...

Medical research

Protein sequences provide clues to how SARS-CoV-2 infects cells

In the early days of the COVID-19 pandemic, it was established that SARS-CoV-2 infects cells by binding to the human protein ACE2, which plays a role in regulating blood pressure. But ACE2 is almost absent in human lung cells, ...

Medical research

Scientists identify synthetic mini-antibody to combat COVID-19

The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the cell surface, the spike protein binds ACE2 using ...

Neuroscience

Should I run or not? The neural basis of aggression and flight

Our brains are wired to protect us from threats. For social animals like humans, threats often come from other members of our own species when there is conflict over food, mates, or territory. Animals with a strong sense ...

Medical research

Fighting cardiovascular disease with acne drug

Dilated cardiomyopathy (DCM) is a leading cause of heart failure, affecting 1 in 250 people. The disease is characterized by an increase in size of the left ventricle of the heart. The stretched heart muscle is then unable ...

Oncology & Cancer

Genome sequencing accelerates cancer detection

Oesophageal cancer is the eighth most common cancer worldwide. It often develops from a condition called Barrett's oesophagus. Existing monitoring and treatment methods are very intrusive, and many patients have to undergo ...

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