Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...
Aug 23, 2022
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Researchers from the group of Eva van Rooij at the Hubrecht Institute have used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced ...
May 24, 2022
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Hypertrophic cardiomyopathy is a heart disease that leads to a stressed, swollen heart muscle. Due to a poor understanding of underlying mechanisms, effective clinical treatments are not available. Patients receive generic ...
May 11, 2022
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Intestinal cells can change specializations during their lives. The BMP signaling pathway—an important communication mechanism between cells—appears to be the driver of these changes. That is what scientists from the ...
Mar 1, 2022
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The research groups of Jeroen Bakkers (Hubrecht Institute/UMC Utrecht) and Toon van Veen (UMC Utrecht) report the first patient-specific model for the heart disease arrhythmogenic cardiomyopathy (ACM). They were able to simulate ...
Dec 9, 2021
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Researchers from the group of Hans Clevers (Hubrecht Institute) developed the first patient-derived organoid model for cervical cancer. They also modeled the healthy human cervix using organoids. In close collaboration with ...
Apr 13, 2021
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Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in ...
Mar 16, 2021
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Researchers from the Hubrecht Institute have mapped the recovery of the heart after a heart attack with great detail. They found that heart muscle cells called cardiomyocytes play an important role in intracellular communication ...
Jan 29, 2021
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Researchers from the group of Catherine Robin at the Hubrecht Institute have characterized the molecular landscape of the aorta that supports the generation of the first hematopoietic stem cells (HSCs) in the embryo. HSCs ...
Jun 5, 2020
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High-grade serous ovarian cancer is the most common type of ovarian cancer, and has the lowest rate of survival. It is often only diagnosed when it has already spread within the pelvis and abdomen, making it harder to treat. ...
May 27, 2020
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