Institute for Quality and Efficiency in Health Care

Medications

Safinamide in Parkinson disease: No hint of added benefit

Safinamide (trade name: Xadago) has been available since February 2015 as add-on therapy for the treatment of mid- to late-stage Parkinson disease in adults. In combination with levodopa alone or together with other Parkinson ...

Medications

Perampanel for epilepsy: Still no proof of added benefit

The drug perampanel (trade name Fycompa) has been approved since July 2012 as adjunctive ("add-on") therapy for adults and children aged 12 years and older with epileptic fits (seizures). In a new early benefit assessment ...

Medications

Nalmefene for alcohol dependence: Added benefit not proven

Nalmefene (trade name Selincro) has been approved since February 2013 for people with alcohol dependence who currently drink a lot of alcohol, but who do not have physical withdrawal symptoms and who do not require immediate ...

Medications

Nivolumab in melanoma: Added benefit in certain patients

Nivolumab (trade name: Opdivo) has been approved since June 2015 for adults with advanced melanoma. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this drug ...

Arthritis & Rheumatism

Rheumatoid arthritis: Biologics in second-line therapy show benefit

The German Institute for Quality and Efficiency in Health Care (IQWiG) examined 9 biotechnologically produced drugs for the treatment of adults with rheumatoid arthritis in whom prior pharmacological treatment had failed. ...

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