Institute for Research in Biomedicine (IRB Barcelona)

Neuroscience

Hypothalamus neurons modulate pancreatic insulin amounts

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of POMC neurons in the hypothalamus that detect and integrate signals related to the body's energy state and ...

Oncology & Cancer

Acidic pH—the weakness of cancer cells

A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, ...

Diseases, Conditions, Syndromes

Scientists discover a potential treatment for cirrhosis

A study by IRB Barcelona and IDIBAPS reveals a therapeutic target to prevent the development of the many abnormal blood vessels that cause gastrointestinal bleeding—the main complication in cirrhosis.

Medical research

Cancer research repurposed to expose age-related blood diseases

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells. Clonal hematopoiesis ...

Oncology & Cancer

Researchers create viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine (IRB Barcelona) led a study in which they designed a new strategy to get genetically modified viruses to selectively ...

Medical research

Shuttling drugs across the blood-brain barrier

The brain is protected by a barrier of cells that tightly regulates the transport of substances into this organ in order to prevent infection. The essential protective function of this barrier is also a red light for 98% ...

Oncology & Cancer

Formation of new blood vessels in tumors regulated by p38 protein

A study performed at the Institute for Research in Biomedicine(IRB Barcelona) and published in the journal Nature Communications demonstrates that inhibition of the p38 protein boosts the formation of blood vessels in human ...

Genetics

Team identifies IL-17 protein as key factor in skin aging

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging. ...

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