Journal of the National Cancer Institute

Oncology & Cancer

Menopausal hormone therapy and breast cancer risk

In the past decade, results from large prospective cohort studies and the Women's Health Initiative (WHI) randomized placebo-controlled hormone therapy trials have substantially changed thoughts about how estrogen alone and ...

Oncology & Cancer

DCIS Score quantifies risk of ipsilateral breast event

The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to ...

Oncology & Cancer

Genetic variants, tobacco exposure and lung cancer risk

There is an association between the rs1051730-rs16969968 genotype and objective measures of tobacco exposure, which indicates that lung cancer risk is largely, if not entirely, mediated by level of tobacco exposure, according ...

Oncology & Cancer

The challenges of cancer vaccines

The first therapeutic cancer vaccine has now been approved by the FDA, and a diverse range of therapeutic cancer vaccines directed against a spectrum of tumor-associated antigens are currently being evaluated in clinical ...

Oncology & Cancer

Cancer screening reform needed

Since the National Cancer Institute developed the first guidelines on mammography screening over thirty years ago, advocacy and professional groups have developed guidelines focused on who should be screened, instead of communicating ...

Oncology & Cancer

Early-life risk factors for non-Hodgkin lymphoma

Factors influencing early life non-Hodgkin lymphoma (NHL) incidence include family characteristics, high fetal growth, older maternal age, low birth order, and male gender, according to a study published May 22 in the Journal ...

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