An analysis of aging in Down syndrome and hypercholesterolemia mouse models has suggested that a Down syndrome-associated gene, DSCR-1, protects against abnormal vascularization of the cornea and associated corneal opacity ...
Nov 6, 2020
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Researchers at Kumamoto University, Japan, have generated mice lacking the estrogen receptor beta (ERĪ²) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration ...
Oct 13, 2020
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A research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells. While attempting to identify the proteins ...
Oct 13, 2020
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A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated ...
Sep 23, 2020
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A joint project led by Kumamoto University (Japan) has discovered a new mechanism for anticancer drug resistance in gastric cancer. Researchers found that the Annexin A6 molecule contained in extracellular vesicles (EVs) ...
Aug 21, 2020
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Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a disease that causes multiple ...
Aug 21, 2020
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Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging. Their experiments ...
Aug 7, 2020
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Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in schizophrenia and bipolar ...
Jul 9, 2020
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Motile sperm are difficult to collect with a conventional cell sorter because they are vulnerable to physical damage. A research collaboration between Kumamoto and Kyoto Universities in Japan has developed a technique that ...
Jul 2, 2020
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A research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes inflammation and oncogenesis. The action of the viral gene HTLV-1 bZIP factor (HBZ) ...
Jun 17, 2020
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