Lunenfeld-Tanenbaum Research Institute

The Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada was established in 1985 by an endowment from the Lunenfeld and Kunin families. It comprises 36 principal investigators, has a budget of C$90 million (2005/6), has over 200 trainees and approximately 600 staff. The Institute conducts research into various forms of cancer (colon, breast, pancreatic, prostate), neurological disorders and brain illnesses, women's and infants' health, diabetes, developmental biology, stem cell biology and tissue regeneration, mouse models of human disease, genomic medicine and systems biology. The Institute has 100,000 sq ft (9,300 m) of space and is split between the main hospital and the Joseph and Wolf Lebovic Health Complex. The founding director was Dr. Louis Siminovitch (1984–1994), followed by Dr. Alan Bernstein (1995–2000), Drs. Janet Rossant and Anthony Pawson (2001–2002), Dr. Anthony Pawson (2002–2005) and Dr. James Woodgett (2005-).


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Oncology & Cancer

New research finds common denominator linking all cancers

All cancers fall into just two categories, according to new research from scientists at Sinai Health, in findings that could provide a new strategy for treating the most aggressive and untreatable forms of the disease.

Medical research

Plugging leaky blood vessels to save vision

A new drug approach has been developed for safer clean-up of deformed blood vessels in the eye by a research team at the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital in Toronto.

Oncology & Cancer

Genetic association with aggressive prostate cancer discovered

An international study published in the Journal of the National Cancer Institute has identified a genetic connection to the aggressive form of prostate cancer. The study showed a threefold increase in the risk of aggressive ...