Microglia, the immune cells of the central nervous system, differ in male and female mice. MDC researchers have reported on the sex-specific features in Cell Reports. Their findings could change how we treat neurological ...
Sep 4, 2018
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143
The exchange of gases between the air we breathe and our blood takes place via alveoli—tiny air sacs in our lungs. For this process to run smoothly, the epithelial cells of the alveoli produce a substance called "surfactant" ...
Sep 16, 2022
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134
How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has ...
Jun 10, 2022
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280
An international research team has succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes ...
Feb 22, 2018
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273
A team of neuroscientists at Max Delbrueck Center for Molecular Medicine in the Helmholtz Association (MDC) have made an unexpected discovery about the way mice perceive warming sensations. It's counterintuitive: cooling ...
Mar 24, 2020
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137
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.
Aug 4, 2022
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18
Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...
Feb 2, 2024
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66
Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, ...
Jul 1, 2020
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8
Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into ...
Dec 13, 2019
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50
Immunotherapy with T-cells offers great hope to people suffering from cancer. Some initial successes have already been made in treating blood cancer, but treating solid tumors remains a major challenge. The signaling molecule ...
Apr 26, 2017
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