RIKEN

Ophthalmology

Improved retinal transplant technique ready for clinical trials

Researchers led by Michiko Mandai at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have used a genetic modification to improve human-derived retina transplants grown in the lab. After transplant into damaged ...

Biomedical technology

The free-energy principle explains the brain

The RIKEN Center for Brain Science (CBS) in Japan, along with colleagues, has shown that the free-energy principle can explain how neural networks are optimized for efficiency. Published in the scientific journal Communications ...

Medications

Cancer therapy using on-site synthesis of anticancer drugs

An international research group at the RIKEN Cluster for Pioneering Research (CPR) has successfully treated cancer in mice using metal catalysts that assemble anticancer drugs together inside the body. Published in the scientific ...

Neuroscience

How the hippocampus orchestrates memory consolidation

A brain region in mice that plays a key role in coordinating the playback process that consolidates memories during sleep has been identified by RIKEN neuroscientists. This finding could have implications for neurological ...

Medical research

New mouse model mimics earliest stages of Alzheimer's disease

Drug hunters hoping to prevent or delay the onset of Alzheimer's disease take note—a new mouse model developed at RIKEN offers a powerful platform for evaluating potential therapies designed to combat the neurodegenerative ...

Oncology & Cancer

GABA released by B-cells blunts the immune response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted ...

Genetics

A genetic brain disease reversed after birth

Researchers at the RIKEN Cluster for Pioneering Research (CPR) in Japan report that Kleefstra syndrome, a genetic disorder that leads to intellectual disability, can be reversed after birth in a mouse model of the disease. ...

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