Researchers from the RIKEN Global Research Cluster in Japan have developed a potential mouse model for the genetic disorder known as an NGLY1 deficiency. Published in the journal PLOS Genetics, the study describes how a complete ...
Apr 21, 2017
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The immune system's first encounter with a potential threat is a valuable learning experience. Through a process of genetic recombination, our immune B cells can potentially produce a wide array of B cell receptor (BCR) molecules, ...
Aug 23, 2013
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The formation of a 'body plan' during embryonic development is driven by the distribution of signaling molecules called morphogens in the embryo, determining front from back and left from right. Atsushi Miyawaki, Satoshi ...
Jun 14, 2013
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An all-RIKEN team of neuroscientists has mapped out neurons in the mouse visual system that are selectively activated during decision-making, and may directly influence this process. To achieve this, they combined a cleverly-crafted ...
Apr 19, 2023
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In the era of molecular medicine, potentially active compounds for use in cancer therapies can be identified faster than ever before. Yet pinpointing the molecular target of an anticancer compound and deducing its mode of ...
Apr 22, 2013
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Three RIKEN neuroscientists have found that rats reinforce the memories of negative experiences in familiar locations by preferentially replaying them over in their minds. This finding could have implications for treating ...
Aug 7, 2023
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Sleep research typically involves recording electroencephalography (EEG) and electromyography (EMG) signals of brain activity over long periods of time, then painstakingly analyzing these records in a process called sleep ...
Aug 2, 2013
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(Medical Xpress)—For many patients with non-small-cell lung carcinoma (NSCLC), tumorigenesis is fueled by mutations that hyperactivate the epidermal growth factor receptor (EGFR) signaling protein. These individuals may ...
Feb 15, 2013
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Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur ...
Dec 20, 2016
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Researchers at the RIKEN Brain Science Institute in Japan have discovered a process through which changes in nutrition during early mouse pregnancy lead to offspring that develop schizophrenic-like symptoms as adults. Published ...
Sep 5, 2017
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