For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor—it performs the crucial task of helping convert DNA ...
Nov 19, 2015
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159
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.
Jul 11, 2011
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Sometimes cancer stays put, but often it metastasizes, spreading to new locations in the body. It has long been suspected that genetic mutations arising inside tumor cells drive this potentially devastating turn of events.
May 25, 2020
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121
The first signs of Huntington's, an inherited disease that slowly deteriorates bodies and minds, don't typically surface until middle age. But new findings suggest that something in the brain might be amiss long before symptoms ...
Sep 17, 2019
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90
In order to kill cancer cells, chemotherapy drugs must first make their way inside them. But cancer cells are shrewd, and some use molecular pumps to expel the drugs before they have a chance to work. New research from Rockefeller's ...
Mar 30, 2018
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168
After 35 years of rigorous research, there is still no cure for HIV. Current drugs can be used to halt the infection, but fall short of reaching hidden reserves of dormant virus that can lurk for life within infected white ...
Apr 24, 2018
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18
As time goes by, the tips of your chromosomes—called telomeres—become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.
Dec 1, 2020
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41
A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate. Without oxygen, ...
Jun 25, 2018
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118
Gene editing technologies developed in the past decade have proven to be extraordinarily powerful and hold the potential to someday cure or prevent a range of diseases. While applications that introduce edits in somatic cells ...
Sep 7, 2020
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10
Like a marching band falling out of step, muscle cells fail to perform in unison in patients with Duchenne muscular dystrophy. A new study in The Journal of Cell Biology reveals how this breakdown leads to the proliferation ...
Oct 14, 2014
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