Genetics
New test for rare disease identifies children who may benefit from simple supplement
The nutritional supplement has dramatically improved the lives of other children with the rare metabolic disorder.
Jun 4, 2020
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Page 6 - Sanford Burnham Prebys Medical Discovery Institute
Oncology & Cancer
Nutritional cues regulate pancreatic tumor's 'cell drinking'
Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging "fuel" through an alternative supply route, called macropinocytosis. Scientists are hopeful that blocking this process, often described as "cellular ...
Jun 27, 2019
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Medical research
Scientists discover new survival strategy for oxygen-starved pancreatic cancer cells
Oxygen is essential to life. When fast-growing tumor cells run out of oxygen, they quickly sprout new blood vessels to keep growing, a process called angiogenesis.
Oct 24, 2019
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Oncology & Cancer
A two-for-one approach to boost melanoma immunotherapy
New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...
Jul 5, 2023
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Genetics
A deep dive into cellular aging
Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell's nucleus—and ...
Feb 20, 2020
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Oncology & Cancer
Scientists shrink pancreatic tumors by starving their cellular 'neighbors'
Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking 'cell drinking,' or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth—providing ...
Mar 17, 2021
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Medical research
Antimicrobial protein implicated in Parkinson's disease
An immune system protein that usually protects the body from pathogens is abnormally produced in the brain during Parkinson's disease, scientists from Sanford Burnham Prebys report. The discovery, published in Free Radical ...
Jul 18, 2019
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Oncology & Cancer
5 things to know about immunotherapy and breast cancer
If you follow news about medical breakthroughs, you have undoubtedly heard about immunotherapy to treat cancer.
Oct 1, 2019
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Oncology & Cancer
Research reveals why some tumors have different makeup of cells
Molecular changes in cells called fibroblasts, which help provide support for tissues throughout the body, may explain why one type of colon cancer doesn't respond to therapy, according to a team of researchers from Weill ...
Nov 26, 2020
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Medical research
New drug combination shows promise as powerful treatment for AML
Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone. The researchers were able to significantly enhance cancer cell death by jointly ...
Jan 19, 2021
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