Sanford Burnham Prebys is a 501(c)(3) non-profit medical research institute focusing on basic and translational research, with major research programs in cancer, neurodegeneration, diabetes, infectious, inflammatory, and childhood diseases. The institute also specializes in stem cell research and drug discovery technologies.
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Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.
Jun 4, 2024
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Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in ...
May 28, 2024
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With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. Most of the focus has been on developing genetic sequencing assays or analyses ...
Apr 18, 2024
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Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...
Apr 16, 2024
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Scientists at Sanford Burnham Prebys have demonstrated that vesicles traveling between cells in the brain carry more complete instructions for altering cellular function than previously thought.
Apr 9, 2024
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For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12—an essential nutrient that supports healthy development and functioning of the central nervous system (CNS)—and multiple ...
Dec 11, 2023
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Viruses have limited genetic material—and few proteins—so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now, in a study published in the journal PLOS Pathogens, researchers ...
Dec 9, 2023
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A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three ...
Nov 14, 2023
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