Page 26 - St. Jude Children's Research Hospital

Diseases, Conditions, Syndromes

Want to block flu transmission? Targeting nasal bacteria may help

Antibiotics won't help you recover from the flu, but an antibiotic ointment helped St. Jude Children's Research Hospital scientists identify a possible strategy for slowing influenza infections. The work appeared in the journal ...

Oncology & Cancer

Team creates resource for pediatric brain tumor research

Scientists at St. Jude Children's Research Hospital have created orthotopic patient-derived xenograft (O-PDX) models representing a variety of pediatric brain tumor types. The models are molecularly characterized and available ...

Oncology & Cancer

CICERO software enables detection of cancer-causing gene fusions

After years of development, engineering and enhancement, researchers at St. Jude Children's Research Hospital have made publicly available a software system that enables better detection of gene fusions. The system, called ...

Medical research

Cytokine implicated in HLH treatment resistance

Scientists at St. Jude Children's Research Hospital, UCSF Benioff Children's Hospitals and Baylor College of Medicine are investigating how to best treat hemophagocytic lymphohistiocytosis (HLH), a rare immune disorder. Their ...

Oncology & Cancer

Identifying survivors at high risk of secondary cancers

Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes. Their results may help predict which survivors are at increased risk of ...

Oncology & Cancer

Targeting a transporter to treat SHH medulloblastoma

Investigators at St. Jude Children's Research Hospital have found that the ABCC4 transporter is critical to the SHH signaling pathway in the brain tumor medulloblastoma. This work provides a rationale for development of small ...

Oncology & Cancer

Mapping genetic variants driving toxicity to leukemia therapy

Scientists at St. Jude Children's Research Hospital, alongside collaborators around the world, have created a comprehensive reference of functional variants in an important drug-metabolizing enzyme called NUDT15. This thorough ...

page 26 from 40