Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA. The tool is an early step in the process to improve the safety and efficacy of gene and ...
Sep 22, 2022
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Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma. The findings will help researchers better understand the biology of the disease, as ...
Sep 21, 2022
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Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death. In doing so, they persist and lead to cancer recurrence. The findings may serve as the basis for ...
Sep 1, 2022
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Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL). The St. Jude Children's Research Hospital study is the first to supply a comprehensive ...
Sep 1, 2022
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When Russian forces invaded Ukraine in February 2022, disruptions in civilian life (particularly to the health care system) created a dire situation for Ukrainian children with cancer and blood disorders. In response, the ...
Sep 1, 2022
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To find new treatment approaches for childhood cancer, scientists at St. Jude Children's Research Hospital are digging deep into disease biology to target a process long considered "undruggable." The approach revealed a new ...
Jul 13, 2022
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Scientists at St. Jude Children's Research Hospital have identified how an appendage on the surface of cells, called the primary cilium, contributes to certain types of medulloblastoma. The study has implications for drug ...
Jul 8, 2022
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Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...
Jun 22, 2022
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Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical. The researchers ...
May 20, 2022
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Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon ...
May 19, 2022
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