Computational scientists at St. Jude Children's Research Hospital have created a tool to find genes and genetic variants that predispose people to rare diseases. Finding genes and genetic variants that contribute to rare ...
May 11, 2022
0
48
Scientists at St. Jude Children's Research Hospital have evaluated how vaccination against, and infection with, SARS-CoV-2 affects the immune system. The results confirm that immunity by infection is not better than vaccination ...
Apr 5, 2022
1
137
Most clinical studies of the immune system use adults. For pediatric cancer patients, that information doesn't tell the full story. Researchers at St. Jude Children's Research Hospital found that the active immune system ...
Feb 7, 2022
0
46
Scientists at St. Jude Children's Research Hospital have developed the first GRP78 targeted chimeric antigen receptor (CAR) T cell. Their GRP78 CAR T cell successfully targeted and destroyed acute myelogenous leukemia (AML) ...
Jan 31, 2022
0
563
Prior infection with coronaviruses that cause the common cold impedes the antibody immune response against SARS-CoV-2, the coronavirus responsible for COVID-19. The results from St. Jude Children's Research Hospital appeared ...
Jan 13, 2022
0
373
Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell identity. Scientists at ...
Jan 11, 2022
0
85
A genomic architectural discovery made deep inside neurons of the brain's movement control center reveals how DNA packaging may contribute to neurodegenerative diseases. St. Jude Children's Research Hospital scientists led ...
Dec 15, 2021
0
52
Survival rates increased about 20% for children with high-risk neuroblastoma enrolled in a St. Jude Children's Research Hospital clinical trial that included a novel monoclonal antibody produced onsite. The findings appeared ...
Dec 6, 2021
0
190
ALK is a receptor tyrosine kinase that regulates important functions in the central nervous system. Scientists at St. Jude Children's Research Hospital have used leading-edge structural biology techniques to reveal in more ...
Nov 24, 2021
0
83
Activating the immune system to battle infections or cancers depends on more than detecting the threat. The immune system must also detect whether its cells have sufficient nutrients to fuel the immune response.
Nov 19, 2021
0
64
