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Oncology & Cancer

Improving immunotherapy for cancer

Our immune system not only protects us against infection, but also against cancer. This powerful protection is based in particular on the activation of special cells of the immune system, CD8+ T cells. These cells recognize ...

Immunology

Nasal smear as an allergy screening test

130 million people in Europe suffer from hay fever and other forms of allergic rhinitis. Until now, these conditions have typically been diagnosed using blood samples or skin prick tests. The latter method is often seen as ...

Medical research

Crohn's disease: Preserving inflammation-free phases

Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. As of now, there is no cure for this disease. A research group led by the Technical University of Munich (TUM) ...

Genetics

Fatal overproduction of antibodies

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils ...

Genetics

New gene correction therapy for Duchenne muscular dystrophy

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of 12 and reducing life expectancy. Researchers at Technical University of ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

Medications

New approach to pain treatment in diseases of the pancreas

One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent ...

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