Page 9 - Technical University Munich

Genetics

Fatal overproduction of antibodies

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils ...

Genetics

New gene correction therapy for Duchenne muscular dystrophy

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of 12 and reducing life expectancy. Researchers at Technical University of ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

Medications

New approach to pain treatment in diseases of the pancreas

One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent ...

Cardiology

Who benefits from a defibrillator?

Implantable defibrillators can save lives, but also harbor risks. A major European study headed by three researchers from the Technical University of Munich (TUM), LMU München and University Medical Center Göttingen has ...

Alzheimer's disease & dementia

Direct toxic action of beta-amyloid identified

Hyperactive neurons in specific areas of the brain are believed to be an early perturbation in Alzheimer's disease. For the first time, a team from the Technical University of Munich (TUM) was able to explain the reasons ...

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