A high-fat diet can carry health risks, but for mothers-to-be, it may make all the difference when it comes to Alzheimer's disease prevention for their children. In a report published online August 26 in the journal Molecular ...
Aug 27, 2019
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776
Sometimes the more a person tries to fix a seemingly minor problem, the worse things become. Cells are no different, it turns out, though attempting to compensate for what begins as a minor deficiency or dysfunction can be ...
Sep 3, 2019
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73
Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons. And similar to other quality control processes, the VPS35 system goes a long way toward protecting ...
Jul 9, 2019
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461
Gene-editing therapy aimed at two targets—HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells—can effectively eliminate HIV infection, new research from the Lewis Katz School ...
May 1, 2023
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128
A NIH-sponsored double-blinded, randomized clinical trial entitled Action to Control Cardiovascular Risk in Diabetes (ACCORD study) came to a halt seven years ago after patients receiving more intensive diabetes therapy were ...
Oct 13, 2015
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6
Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses. Now, scientists at the Lewis Katz School of Medicine at Temple University have ...
May 19, 2023
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Like catching two fish with one worm, treating two problems with a single drug is efficient, but exceedingly difficult. In particular, for new diabetes medications, in which one drug aims to tackle two major complications ...
Sep 25, 2019
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132
Like power lines in an electrical grid, long wiry projections that grow outward from neurons—structures known as axons—form interconnected communication networks that run from the brain to all parts of the body. But unlike ...
Apr 30, 2020
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391
By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function. ...
Jun 21, 2019
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The immune system is like a carefully regulated machine, complete with its own built-in "brakes" that prevent it from overreacting and causing excess inflammation in otherwise healthy tissues. This preventative safety net, ...
Mar 25, 2020
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