Under stress, the human heart struggles to pump blood efficiently through the body. Over time, as the heart overexerts itself trying to make up for this lost efficiency, harmful changes take place. The most worrisome of these ...
Mar 15, 2022
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Researchers at the Lewis Katz School of Medicine at Temple University have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human embryonic stem cells (hESCs) for a process essential ...
Feb 10, 2022
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With age, the human heart gradually loses its ability to repair itself following injury. Damage wrought by injuries such as cardiac ischemia and heart attack, which are associated with decreased oxygen levels in the heart, ...
Oct 21, 2021
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Red blood cells in the human body are continuously subjected to oxidative stress, in which highly reactive molecules damage cellular components. Blood cells have a mechanism in place to deal with this stress, an enzyme called ...
Sep 27, 2021
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Like highways, roads, and side streets, blood vessels in the human body come in different sizes, with a range of traffic-carrying capacities. These differences are critical to facilitating blood flow through tissues. But ...
Sep 23, 2021
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Like a blocked water line, obstructions in blood vessels in the human circulatory system can cause serious problems. This is especially the case in superior vena cava syndrome (SVCS), in which oxygen-depleted blood returning ...
Jun 28, 2021
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For patients with chronic pain, ineffective treatments, lowered work productivity, and other factors often coalesce, fueling feelings of hopelessness and anxiety and setting the stage for even bigger problems, including substance ...
May 5, 2021
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About 6.2 million Americans suffer from heart failure, an incurable disease with a staggering mortality rate—some 40 percent of patients die within five years of diagnosis. Heart failure is one form of heart disease for ...
Mar 12, 2021
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While the COVID-19 pandemic brought most of the country to a standstill in March 2020, Philadelphia trauma surgeons noticed an alarming trend in the incidence of firearm violence. Instead of decreasing with containment measures, ...
Feb 10, 2021
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Like a failing fuel pump that causes a loss of engine power in a car, a diseased heart can take a serious toll on the body's performance. For some patients, tasks like walking up a flight of stairs or walking across a room ...
Jan 13, 2021
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