The capacity of the human central nervous system to regenerate after injury or illness is limited, and the resulting functional impairments carry a vast societal and personal burden. In glaucoma, degeneration of retinal ganglion ...
Jul 2, 2019
0
0
Alcohol consumption during pregnancy has been linked to poor growth of the placenta, causing conditions such as fetal growth restriction and low birth weight. Although most women cease drinking once they know they are pregnant, ...
Jun 10, 2019
0
261
Advances in optimisation of the gene-editing technique CRISPR/Cas9 in zebrafish disease models offer a new level of accuracy and specificity previously out of reach for research into human genetic disorders.
Oct 18, 2018
0
0
Scientists rely on the use of animal models to improve our understanding of lethal muscle-wasting disease Duchenne muscular dystrophy (DMD), and to develop safe new therapies. A newly developed rabbit model, created through ...
Jun 4, 2018
0
2
The chronic pain experienced by a number of patients with diabetes has widely been assumed to originate from damage to blood vessels or to local tissue surrounding neurons caused by high blood-sugar levels. However, a new ...
May 10, 2018
0
23
Current treatments may be administered too late to target Friedreich's ataxia effectively. New research using a slow-onset frataxin knock-in/knockout mouse model showed significantly reduced levels of mitochondrial biosynthesis ...
Nov 8, 2017
0
0
New research into Rett syndrome therapeutics suggests that a small molecule already reported to improve respiratory problems associated with the disease may also improve spatial memory and motor skill defects.
Jul 5, 2017
0
3
Alterations in social behaviour, including aggression, are associated with a number of neuropsychiatric disorders such as schizophrenia and bipolar disorder. Along with DiGeorge syndrome and velo-cardio-facial syndrome, these ...
Jun 7, 2017
0
0
A growing aging population means that age-dependent neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis are affecting increasing numbers of ...
May 3, 2017
0
2
Scientists at KU Leuven (University of Leuven), Belgium, have succeeded in growing three-dimensional cultures of the endometrium, the uterus' inner lining, in a dish. These so-called endometrial organoids promise to shed ...
Apr 25, 2017
0
1
