A team led by Massimo Squatrito, Head of the Seve Ballesteros Foundation Brain Tumor Group at the Spanish National Cancer Research Centre (CNIO), has made important findings of how some gliomas can acquire chemoresistance. ...
Aug 4, 2020
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Researchers at the CNIO (Spanish National Cancer Research Center) have discovered that one of the causes for the rare tumor pheochromocytoma-paraganglioma is the interruption of a very specific step in the production of some ...
May 9, 2023
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At 18 Spanish hospitals, when a patient with brain metastasis undergoes surgery, they can donate a tiny part of their brain to the first repository of brain metastasis living samples in the world, based at CNIO (Spanish National ...
Oct 31, 2023
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The intestine is very susceptible and is affected by the harsh conditions caused by DNA-altering agents, such as radiation and chemotherapy, during cancer treatment. For example, many patients with tumors in the gastrointestinal ...
Sep 14, 2022
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Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage is to prevent the two DNA strands from separating so that the cellular machinery cannot read the instructions written ...
Jun 15, 2021
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Precision medicine seeks to adapt treatments to the characteristics of each patient. Genome studies are providing more and more data to achieve this, but this very abundance of information is hampering the task: Doctors must ...
Jun 20, 2023
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The KRAS oncogene is involved in at least one fifth of all human cancers: KRAS mutations are directly responsible for 32% of lung tumors and 96% of pancreatic tumors. However, after more than thirty years of research to date, ...
Sep 9, 2020
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Capecitabine is a chemotherapy drug used for breast and colorectal cancer. It can extend survival rate by nearly 10%. However, recent studies revealed that almost 50% of patients develop palmar-plantar erythrodysesthesia, ...
Sep 21, 2020
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15 years ago, a woman in her thirties was diagnosed with metastatic kidney cancer. The oncologist José Pablo Maroto, from the Hospital de la Santa Creu i Sant Pau, in Barcelona, decided to treat her with the drug temsirolimus, ...
Jun 14, 2023
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The Cell Division and Cancer Group of the Spanish National Cancer Research Centre (CNIO) has discovered that MASTL, a protein whose function has not yet been sufficiently investigated, plays an important role in controlling ...
Nov 1, 2018
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