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Oncology & Cancer

Strengthening artificial immune cells to fight cancer

Among available immunotherapies, the use of CAR T cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, ...

Diseases, Conditions, Syndromes

Research team confirms immunity to COVID-19 reduces contagiousness

Nearly one in three people exposed to SARS-CoV2 is infected, and as many as two in five with the omicron variant. In the case of immunity—conferred by vaccination, infection or a combination of the two—this rate drops ...

Genetics

Gene responsible for severe facial defects identified

Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are ...

Medical research

How opioid drugs get into our cells

The human body naturally produces opioid-like substances, such as endorphins, that block the perception of pain and increase the feeling of well-being. Similarly, opioid drugs, including morphine or fentanyl, are widely used ...

Oncology & Cancer

Allies or enemies of cancer: The dual fate of neutrophils

Why do cancer immunotherapies work so extraordinarily well in a minority of patients, but fail in so many others? By analyzing the role of neutrophils, immune cells whose presence usually signals treatment failure, scientists ...

Neuroscience

How to generate new neurons in the brain

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...

Alzheimer's disease & dementia

An action plan to prevent Alzheimer's disease

Memory loss, behavioral changes, cognitive deficits: Alzheimer's disease leads to a dramatic loss of autonomy for those affected and has a heavy impact on health costs. Its prevention has become a real social challenge. An ...

Oncology & Cancer

Fighting cancer is more efficient at dawn, study finds

The ability of tumors to take hold and grow depends, among other things, on the effectiveness of the immune system in fighting them. Cancer cells, like pathogens, can be identified and targeted by a specific immune response. ...

Medical research

Overcoming resistance to colon cancer treatment

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs. ...

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