University of Geneva

Oncology & Cancer

Allies or enemies of cancer: The dual fate of neutrophils

Why do cancer immunotherapies work so extraordinarily well in a minority of patients, but fail in so many others? By analyzing the role of neutrophils, immune cells whose presence usually signals treatment failure, scientists ...

Neuroscience

How to generate new neurons in the brain

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...

Alzheimer's disease & dementia

An action plan to prevent Alzheimer's disease

Memory loss, behavioral changes, cognitive deficits: Alzheimer's disease leads to a dramatic loss of autonomy for those affected and has a heavy impact on health costs. Its prevention has become a real social challenge. An ...

Oncology & Cancer

Fighting cancer is more efficient at dawn, study finds

The ability of tumors to take hold and grow depends, among other things, on the effectiveness of the immune system in fighting them. Cancer cells, like pathogens, can be identified and targeted by a specific immune response. ...

Medical research

Overcoming resistance to colon cancer treatment

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs. ...

Psychology & Psychiatry

Too much motivation affects our decision-making

In a good or a bad mood, focused or distracted, our internal states directly influence our perceptions and decision-making. While the role of motivation on the performance of behavioral tasks has been known for more than ...

Genetics

Zinc could treat a rare genetic disorder

Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene. In order to understand the ...

Medical research

Awakening dormant cells to fight cancer

The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable ...

Diabetes

Diabetes: When circadian lipid rhythms go wrong

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of ...

Medical research

Diabetes: A step closer to a life without insulin

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive. ...

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