Heart defects are the most common type of birth defect, and can be caused by mutations in the gene CHD4. Researchers at the UNC School of Medicine have now revealed key molecular details of how CHD4 mutations lead to heart ...
Jun 12, 2018
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Every year, falls lead to hospitalization or death for hundreds of thousands of elderly Americans. Standard clinical techniques generally cannot diagnose balance impairments before they lead to falls. But researchers from ...
Apr 20, 2017
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Why do some cancers spread rapidly to other organs and others don't metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin ...
Jun 11, 2012
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Insulin resistance affects tens of millions of Americans and is a big risk factor for heart disease. Yet, some people with the condition never develop heart disease, while some experience moderate coronary blockages. Others, ...
Jul 6, 2015
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A newly developed immunotherapy that simultaneously uses modified immune-fighting cells to home in on and attack two antigens, or foreign substances, on cancer cells was highly effective in mice implanted with human neuroblastoma ...
Sep 23, 2021
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Researchers at the UNC School of Medicine conducted a comprehensive genetic analysis of invasive bladder cancer tumors to discover that the disease shares genetic similarities with two forms of breast cancer. The finding ...
Feb 11, 2014
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Eating food and absorbing its nutrients is an everyday occurrence, but this normal activity can look different for someone who suffers from inflammatory bowel disease. IBD, which includes Crohn's disease and ulcerative colitis, ...
Dec 9, 2023
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A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on ...
Feb 28, 2024
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University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that ...
Mar 17, 2016
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A new study by UNC researchers, based on MRI brain scans of 152 infants, found disruptions in functional connectivity within part of the amygdala-prefrontal network - a pathway thought to play an important role in arousal ...
Apr 7, 2015
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