Immunology

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...

Medical research

New approach to treating osteoarthritis advances

The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body's millions of cells. The molecule most used to ...

Medical research

New pharmaceutical target reverses osteoporosis in mice

Biomedical engineers at Duke University have discovered a pharmaceutical target that, when activated, can reverse bone degradation caused by osteoporosis in mouse models of the disease.

Neuroscience

How the brain reacts to sleep deprivation

In a new study, scientists from Forschungszentrum J├╝lich together with partners from the German Aerospace Center (DLR) have investigated the molecular changes with which the human brain reacts to exceptionally long wake ...

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